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CAPTCHA remains by far the most problematic item reported by respondents. “Screens or parts of screens that change unexpectedly” has seen a significant increase over the years and is now reported as the 2nd most problematic item. This likely is due to the dynamic and complex nature of modern web pages and application.
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Curated by Lifekludger, for full post see Source: WebAIM: Screen Reader User Survey #7 Results